Abstract
IT is generally accepted that lymphocyte reactions such as the mitogenic response to concanavalin A (con A) and phytohaemagglutinin (PHA), the graft versus host (GvH) reaction, the helper effect in the antibody response and cell-mediated cytotoxicity (CMC) all involve the activity of thymus-derived lymphocytes (T cells). Because of the paucity of techniques for identifying cells with different functions, however, very little is known about the identity and relationships of T cells involved in these reactions.
Similar content being viewed by others
References
Kisielow, P., et al., Nature 255, 219–220 (1975).
Hirst, J. A., Beverley, P. C. L., Kisielow, P., Hoffman, M. K., and Oettgen, H. F., J. Immun., 115, 1555–1557 (1975).
Raff, M. C., Nase, S., and Mitchison, N. A. Nature, 230, 50–51 (1971).
Takahashi, T., Old, L. J., Hsu, C. J., and Boyse, E. A., Eur. J. Immun., 1, 478–482 (1971).
Shigeno, N., Hämmerling, U., Arpels, C., Boyse, E. A., and Old, L. J., Lancet, ii, 320–325 (1968).
De Sousa, M. A. B., Parrott, D. M. V., and Pantelouris, E. M., Clin. exp. Immun, 4, 637–644 (1969).
Pritchard, H., and Micklem, H. S., Clin. exp. Immun., 14, 597–607 (1973).
Loor, F., and Kindred, B., J. exp. Med., 138, 1044–1055 (1973).
Kisielow, P., and Shiku, H., Arch. Immun. ther. Exp. (in the press).
Shiku, H., et al. J. exp. Med., 141, 227–241 (1975).
Cantor, H., and Boyse, E. A., J. exp. Med., 141, 1376–1399 (1975).
Workshop on non-T cytotoxicity in vitro. In Progress in Immunology II 3 (edit. by Brent, L., and Holborow, J.), 347–350 (North-Holland, Amsterdam; Elsevier, New York, 1974).
Elliott, B. E., and Haskill, J. S., Nature, 252, 607–608 (1974).
Dennert, G., and Hatlen, L. E., Nature, 257, 486–488 (1975).
Howe, M., Beerman, L., and Cohen, C. J. Immun., 111, 1243–1249 (1973).
Janeway, C. A., Sharrow, S. O., and Simpson, E., Nature, 253, 544–546 (1975).
Boyse, E. A., Itakura, K., Stockert, E., Iritani, C. A., and Miura, M., Transplantation, 11, 351–353 (1971).
Sullivan, K. A., Berke, G., and Amos, D. B., Transplantation, 16, 388–391 (1973).
Ford, C. E., Micklem, H. S., Evans, E. P., Gray, J. G., and Ogden, D. A., Ann N. Y. Acad. Sci., 129, 283–290 (1966).
Greaves, M. F., Owen, J. J. T., and Raff, M. C. T and B Lymphocytes (Excerpta Medica, Amsterdam, 1973).
Shiku, H., Bean, M. A., Old, L. J., and Oettgen, H. F., J. natn. Cancer Inst., 54, 415–425 (1975).
Hoffmann, M. K., and Kappler, J. W., J. exp. Med., 137, 721–739 (1973).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
KISIELOW, P., SHIKU, H. & HIRST, J. A new differentiation antigen defining a subpopulation of mouse T cells. Nature 261, 137–139 (1976). https://doi.org/10.1038/261137a0
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1038/261137a0
- Springer Nature Limited
This article is cited by
-
Proceedings of the Conference “Lymphocyte Development, Tolerance and Autoimmunity: Solved and Open Questions”, Held at the Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, on May 12, 2011 (Wrocław, Poland)
Archivum Immunologiae et Therapiae Experimentalis (2011)