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Raman spectra of transfer RNAs with ultraviolet lasers

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Abstract

WE suggest here a new use for Raman spectroscopy in structural studies of nucleic acids. We demonstrate that an enhanced vibrational Raman spectrum of a certain limited portion of an amino acid transfer RNA (tRNA) macromolecule can be observed, if a proper ultraviolet laser beam is chosen for excitation.

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References

  1. Tsuboi, M., Takahashi, S., Muraishi, S., Kajiura, T., and Nishimura, S., Science, 174, 1142–1144 (1971).

    Article  ADS  CAS  Google Scholar 

  2. Small, E. W., and Peticolas, W. L., Biopolymers, 10, 1377–1416 (1971).

    Article  CAS  Google Scholar 

  3. Thomas, G. J., Medeiros, G. C., and Hartman, K. A., Biochim. biophys. Acta, 277, 71–79 (1972).

    Article  CAS  Google Scholar 

  4. Thomas, G. J., Chen, M. C., and Hartman, K. A., Biochim. biophys. Acta, 324, 37–49 (1973).

    Article  CAS  Google Scholar 

  5. Chen, M. C., and Thomas, G. J., Biopolymers, 13, 615–626 (1974).

    Article  CAS  Google Scholar 

  6. Dobek, A., Patkowski, A., Labuda, D., and Augustyniak, J., J. Raman Spectrosc., 3, 45–54 (1975).

    Article  ADS  CAS  Google Scholar 

  7. Yaniv, M., Favre, A., and Barrell, B. G., Nature, 223, 1331–1335 (1969).

    Article  ADS  CAS  Google Scholar 

  8. Bergstrom, D. E., and Leonard, N. J., Biochemistry, 11, 1–8 (1972).

    Article  CAS  Google Scholar 

  9. RajBhandary, U. L., et al., Fedn Proc., 28, 409–409 (1969).

    Google Scholar 

  10. Goodman, H. M., Abelson, J. N., Landy, A., Zadrezil, S., and Smith, J. D., Eur. J. Biochem., 13, 461–483 (1970).

    Article  CAS  Google Scholar 

  11. Ohashi, Z., Harada, F., and Nishimura, S., FEBS Lett., 20, 239–241 (1972).

    Article  CAS  Google Scholar 

  12. Kiefer, W., and Bernstein, H. J., J. appl Spectrosc., 25, 500–501 (1971).

    Article  ADS  CAS  Google Scholar 

  13. Squires, C., and Carbon, J., Nature new Biol., 233, 274–277 (1971).

    Article  CAS  Google Scholar 

  14. Nishimura, S., Progr. nucl. Acid Res. molec. Biol., 12, 49–85 (1972).

    Article  CAS  Google Scholar 

  15. Oshima, T., Sakaki, Y., Wakayama, N., Watanabe, K., Ohashi, Z., and Nishimura, S., Experientia (in the press).

  16. Oshima, T., and Imahori, K., Int. J. system. Bacteriol., 24, 102–112 (1974).

    Article  CAS  Google Scholar 

  17. RajBhandary, U. L., and Chang, S. H., J. biol. Chem., 243, 598–608 (1968).

    CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Faculty of Pharmaceutical Sciences, University of Tokyo, Hongo, Bunkyo-ku, Tokyo

    YOSHIFUMI NISHIMURA, AKIKO Y. HIRAKAWA & MASAMICHI TSUBOI

  2. National Cancer Center, Research Institute, Chuo-ku, Tokyo, Japan

    SUSUMU NISHIMURA

Authors
  1. YOSHIFUMI NISHIMURA
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  2. AKIKO Y. HIRAKAWA
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  3. MASAMICHI TSUBOI
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  4. SUSUMU NISHIMURA
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NISHIMURA, Y., HIRAKAWA, A., TSUBOI, M. et al. Raman spectra of transfer RNAs with ultraviolet lasers. Nature 260, 173–174 (1976). https://doi.org/10.1038/260173a0

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  • DOI: https://doi.org/10.1038/260173a0

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