Abstract
THE primer for the initiation of DNA synthesis by the RNA-directed DNA polymerase (reverse transcriptase) on Rous sarcoma virus (RSV) 70S RNA has been identified as tryptophan tRNA1,2. The RNA primer hybridises efficiently to 35S RNA subunits produced by denaturation of 70S RNA from RSV3 or avian myeloblastosis virus (AMV)4; these template–primer complexes are active in the initiation of DNA synthesis by reverse transcriptase3–5.
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EIDEN, J., QUADE, K. & NICHOLS, J. Interaction of tryptophan transfer RNA with Rous sarcoma virus 35S RNA. Nature 259, 245–247 (1976). https://doi.org/10.1038/259245a0
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DOI: https://doi.org/10.1038/259245a0
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