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Immunological cross reactivity between testicular androgen-binding protein and serum testosterone-binding globulin

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Abstract

WE have reported the presence of a testicular androgen-binding protein (ABP) which is secreted into the testicular fluid of several mammalian species1. ABP is produced by the Sertoli cells and is specifically stimulated by follicle stimulating hormone (FSH)1–7. It is found in particularly high concentrations (3×10−7 M) in the efferent duct fluid of rabbits.

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References

  1. Hansson, V., Ritzen, E. M., French, F. S., and Nayfeh, S. N., in Handbook of Physiology, 5 (edit. by Hamilton, D. W., and Greep, R. O.), 173 (American Physiological Society, 1975).

    Google Scholar 

  2. Hansson, V., et al., Nature new Biol., 246, 56 (1973).

    Article  CAS  Google Scholar 

  3. Hansson, V., et al., Nature, 250, 387 (1974).

    Article  ADS  CAS  Google Scholar 

  4. Hagenäs, L., et al., Molec. cell. Endocr., 2, 339 (1975).

    Article  Google Scholar 

  5. Vernon, R. G., Kopec, B., and Fritz, I. B., Molec. cell. Endocr., 1, 167 (1974).

    Article  CAS  Google Scholar 

  6. Sanborn, B. M., Elington, J. S. H., Chowdbury, M., Tcholakian, R. K., and Steinberger, E., Endocrinology, 96, 304 (1975).

    Article  CAS  Google Scholar 

  7. Tindall, D. J., Schrader, W. T., and Means, A. R., in Hormone Binding and Target Cell Activation in the Testis (edit. by Dufau, M. L., and Means, A. R.), 167 (Plenum, New York, 1974).

    Book  Google Scholar 

  8. Hansson, V., et al., Steroids, 22, 185 (1973).

    Article  CAS  Google Scholar 

  9. Rosner, W. R., and Darmstad, A., Endocrinology, 92, 1700 (1973).

    Article  CAS  Google Scholar 

  10. Mahoudeau, T. A., and Corvol, P., Endocrinology, 92, 1700 (1973).

    Article  Google Scholar 

  11. Hansson, V., et al., Endocrinology, 95, 690 (1974).

    Article  CAS  Google Scholar 

  12. Hansson, V., Ritzen, E. M., French, F. S., Weddington, S. C., and Nayfeh, S. N., Molec. cell. Endocr., 3, 1 (1975).

    Article  CAS  Google Scholar 

  13. Weddington, S. C., et al., Hormonal Regulation of Spermatogenesis (edit. by French, F. S., Hansson, V., Nayfeh, S. N., and Ritzen, E. M.) (Plenum, New York, 1975).

    Google Scholar 

  14. Brandtzaeg, P., Fjellanger, I., and Gjeruldsen, S. T., in Scand. J. Haematol. Suppl., 12, 13 (1970).

    Google Scholar 

  15. Ritzen, E. M., French, F. S., Weddington, S. C., Nayfeh, S. N., and Hansson, V., J. biol. Chem., 249, 6597 (1975).

    Google Scholar 

  16. Setchell, B. P., and Waites, G. M. H., in Handbook of Physiology, 5 (edit. by Hamilton, D. W., and Greep, R. O.), 143 (American Physiological Society, 1975).

    Google Scholar 

  17. Fritz, I. B., Kopec, B., Lam, K., and Vernon, G., in Hormone Binding and Target Cell Activation in the Testis (edit. by Dufau, M. L., and Means, A. R.), 311 (Plenum, New York, 1974).

    Book  Google Scholar 

  18. Sanborn, B., Elkington, J. S. H., Steinberger, E., Steinberger, A., and Meistrich, M. L. in Hormonal Regulation of Spermatogenesis (edit. by French, F. S., Hansson, V., Naufeh, S. N., and Ritzen, E. M.) (Plenum, New York, 1975).

    Google Scholar 

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Authors and Affiliations

  1. Institute of Pathology, Rikshospitalet, Oslo, 1, Norway

    S. C. WEDDINGTON, P. BRANDTZAEG & V. HANSSON

  2. Departments of Pediatrics and Biochemistry and Laboratories for Reproductive Biology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, 27541

    F. S. FRENCH, P. PETRUSZ & S. N. NAYFEH

  3. Pediatric Endocrinology Unit, Clinical Research Laboratory, Karolinska Sjukhuset, Stockholm, Sweden

    E. M. RITZEN

Authors
  1. S. C. WEDDINGTON
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  2. P. BRANDTZAEG
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  3. V. HANSSON
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  4. F. S. FRENCH
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  5. P. PETRUSZ
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  6. S. N. NAYFEH
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  7. E. M. RITZEN
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WEDDINGTON, S., BRANDTZAEG, P., HANSSON, V. et al. Immunological cross reactivity between testicular androgen-binding protein and serum testosterone-binding globulin. Nature 258, 257–259 (1975). https://doi.org/10.1038/258257a0

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  • DOI: https://doi.org/10.1038/258257a0

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