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Amplification of a specific region of the polyoma virus genome

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Abstract

Defective DNAs, isolated from mouse cells after infection with a clonally purified stock of defective polyoma virus, have been found to consist of nucleotide sequences from about 17% of the wild-type polyoma genome, tandemly repeated two to six times. These sequences come from the region of the viral DNA which contains the origin of DNA replication and the 5′ ends of early and late stable mRNAs.

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Authors and Affiliations

  1. Imperial Cancer Research Fund, PO Box 123, Lincoln's Inn Fields, London, WC2A 3PX, UK

    Beverly E. Griffin & Mike Fried

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  1. Beverly E. Griffin
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  2. Mike Fried
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Griffin, B., Fried, M. Amplification of a specific region of the polyoma virus genome. Nature 256, 175–179 (1975). https://doi.org/10.1038/256175a0

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  • DOI: https://doi.org/10.1038/256175a0

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