Skip to main content
SpringerLink
Log in

Glucagon-like immunoreactivity in insect corpus cardiacum

  • Letter
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

SINCE Steele attributed hyperglycaemic activity to the corpus cardiacum of the cockroach neurosecretory system1–3, it has been demonstrated in other species of Orthoptera4–10 and in Diptera11,12 and Hymenoptera13. Although extracts of corpora cardiaca from the blowflies Phormia11 and Calliphora14 and the silk moth Cecropia15 seem to be inactive, the hyperglycaemic hormone is liberated from the Calliphora gland by electrical12 or mechanical14 stimulation in situ. Similarly, extracts from Locusta6,16 and Phormia11 are poorly active intraspecifically, but are hyperglycaemic when injected into the cockroach. The nutritional state of the recipient is apparently crucial in determining the extent of the response11.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Steele, J. E., Nature, 192, 680–681 (1961).

    Article  ADS  Google Scholar 

  2. Steele, J. E., Gen. comp. Endocr., 3, 46–52 (1963).

    Article  CAS  Google Scholar 

  3. Goldsworthy, G. J., and Mordue, W., J. Endocr., 60, 529–558 (1974).

    Article  CAS  Google Scholar 

  4. Bowers, W. S., and Friedman, S., Nature, 198, 685 (1963).

    Article  ADS  CAS  Google Scholar 

  5. Wiens, A. W., and Gilbert, L. I., J. Insect Physiol., 13, 779–794 (1967).

    Article  CAS  Google Scholar 

  6. Goldsworthy, G. J., J. Insect Physiol., 15, 2131–2140 (1969).

    Article  CAS  Google Scholar 

  7. Keeley, L. L., and Friedman, S., Gen. comp. Endocr., 8, 129–134 (1967).

    Article  CAS  Google Scholar 

  8. Brown, B. E., Gen. comp. Endocr., 5, 387–401 (1965).

    Article  CAS  Google Scholar 

  9. Dutrieu, J., and Gourdoux, L., C. r. hebd. Séanc. Acad. Sci., 265, 1067–1070 (1967).

    CAS  Google Scholar 

  10. Natalizi, G. M., Pansa, M. C., D'Ajello, V., Casaglia, O., Bettini, S., and Frontali, N., J. Insect Physiol., 16, 1827–1836 (1970).

    Article  Google Scholar 

  11. Friedman, S., J. Insect Physiol., 13, 397–405 (1967).

    Article  CAS  Google Scholar 

  12. Normann, T. C., and Duve, H., Gen. comp. Endocr., 12, 449–459 (1969).

    Article  CAS  Google Scholar 

  13. Natalizi, G. M., and Frontali, N., J. Insect Physiol., 12, 1279–1287 (1966).

    Article  Google Scholar 

  14. Vejbjerg, K., and Norman, T. C., J. Insect Physiol., 20, 1189–1192 (1974).

    Article  CAS  Google Scholar 

  15. Wiens, A. W., and Gilbert, L. I., Comp. Biochem. Physiol., 21, 145–159 (1967).

    Article  CAS  Google Scholar 

  16. Mordue, W., and Goldsworthy, G. J., Gen. comp. Endocr., 12, 360–369 (1969).

    Article  CAS  Google Scholar 

  17. Goldsworthy, G. J., J. Insect Physiol., 15, 2131–2140 (1969).

    Article  CAS  Google Scholar 

  18. Goldsworthy, G. J., Gen. comp. Endocr., 14, 78–85 (1970).

    Article  CAS  Google Scholar 

  19. Bromer, W. W., Sinn, L. G., and Behrens, O. K., J. Am. chem. Soc., 79, 2807–2810 (1957).

    Article  CAS  Google Scholar 

  20. Thomsen, J., Kristiansen, K., Brunfeldt, K., and Sundby, F., FEBS Lett., 21, 315–319 (1972).

    Article  CAS  Google Scholar 

  21. Bromer, W. W., Boncher, M. E., and Koffenberger, J. E., Jr., J. biol. Chem., 246, 2822–2827 (1971).

    CAS  PubMed  Google Scholar 

  22. Dayhoff, M. O. (ed.), in Atlas of protein sequence and structure, 5, D–8 (National Biomedical Research Foundation, Silver Spring, Maryland, 1972).

  23. Sundby, F., Frandsen, E. K., Thomsen, J., Kristiansen, K., and Brunfeldt, K., FEBS Lett., 26, 289–293 (1972).

    Article  CAS  Google Scholar 

  24. McLaughlin, P. J., and Dayhoff, M. O., in Atlas of protein sequence and structure, 5 (edit. by Dayhoff, M. O.), 50 (National Biomedical Research Foundation, Silver Spring, Maryland, 1972).

    Google Scholar 

  25. Tager, H. S., and Steiner, D. F., Proc. natn. Acad. Sci. U.S.A., 70, 2321–2325 (1973).

    Article  ADS  CAS  Google Scholar 

  26. Ralph, C. L., and McCarthy, R., Nature, 203, 1195–1196 (1964).

    Article  ADS  Google Scholar 

  27. Highnam, K. C., and Goldsworthy, G. J., Gen. comp. Endocr., 18, 83–88 (1972).

    Article  CAS  Google Scholar 

  28. Ornstein, L., and Davis, J. B., Disc electrophoresis (Distillation Products Industries, Rochester, New York, 1962).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Biochemistry, University of Chicago, Chicago, Illinois, 60637

    H. S. TAGER & J. MARKESE

  2. US Grain Marketing Research Center, Agricultural Research Service, US Department of Agriculture, Manhattan, Kansas, 66502

    R. D. SPIERS & K. J. KRAMER

Authors
  1. H. S. TAGER
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. MARKESE
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. R. D. SPIERS
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. K. J. KRAMER
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

TAGER, H., MARKESE, J., SPIERS, R. et al. Glucagon-like immunoreactivity in insect corpus cardiacum. Nature 254, 707–708 (1975). https://doi.org/10.1038/254707a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/254707a0

  • Springer Nature Limited

This article is cited by

Search

Navigation