Skip to main content
Log in

H1 and H2 receptors in the histamine-induced accumulation of cyclic AMP in guinea pig brain slices

  • Letter
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

EVIDENCE has accumulated suggesting that several transmitters, as well as hormonal substances, mediate their actions on effector cells by an increase in the intracellular level of adenosine cyclic 3′,5′-monophosphate (cyclic AMP)1.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Rall, T. W., Pharmac. Rev., 24, 399–409 (1972).

    CAS  Google Scholar 

  2. Forn, J., and Krishna, G., Pharmacology, 5, 193–204 (1971).

    Article  CAS  Google Scholar 

  3. Phyllis, J. W., Tebecis, A. K., and York, D.H., Br. J. Pharmac., 33, 426 (1968).

    Google Scholar 

  4. Cohn, C. K., Ball, C. G., and Hirsch, J., Science, 180, 757 (1973).

    Article  ADS  CAS  Google Scholar 

  5. Schultz, J., and Daly, J. W., J. biol. Chem., 248, 843–852 (1973).

    CAS  PubMed  Google Scholar 

  6. Ash, A. S. F., and Schild, H. O., Br. J. Pharmac. Chemother., 27, 427–439 (1966).

    Article  CAS  Google Scholar 

  7. Black, J. W., Duncan, W. A. M., Durant, C. J., Ganellin, C. R., and Parsons, E. M., Nature, 236, 385–390 (1972).

    Article  ADS  CAS  Google Scholar 

  8. Dousa, T. P., and Code, C. F., Int. Symp. on Histamine H2-Receptor Antagonists, 319–330 (London, 1973).

    Google Scholar 

  9. Brown, B. L., Albano, J. D. M., Ekins, R. P., and Sgherzi, A. M., Biochem., J., 121, 561–562 (1971).

    Article  CAS  Google Scholar 

  10. Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J., J. biol. Chem., 193, 265–275 (1951).

    CAS  Google Scholar 

  11. Black, J. W., Duncan, W. A. M., Emmett, J. C., Ganellin, C. R., Hesselbo, T. M. E., and Wyllie, J. H., Agents and Actions, 3, 133–137 (1973).

    Google Scholar 

  12. Chasin, M., Mamrak, F., Samaniego, S. G., and Hess, S. M., J. Neurochem, 21, 1415–1428 (1973).

    Article  CAS  Google Scholar 

  13. Clark, R. B., and Perkins, J. P., Proc. natn. Acad. Sci. U.S.A., 68, 2757–2760 (1971).

    Article  ADS  CAS  Google Scholar 

  14. Rocha E Silva, M., Chemotherapia, 3, 544–559 (1961).

    Article  Google Scholar 

  15. Brimble, M. J., and Wallis, D. I., Nature, 246, 156–158 (1973).

    Article  ADS  CAS  Google Scholar 

  16. Von Hungen, K., and Roberts, S., Eur. J. Biochem., 36, 391–401 (1973).

    Article  CAS  Google Scholar 

  17. Schwartz, J. C., Julien, C., Feger, J., and Garbarg, M., Fedn. Proc., 33, No. 3, 285 (1974).

    Google Scholar 

  18. Garbarg, M., Barbin, G., Feger, J., and Schwartz, J. C., Science, 186, 833–835 (1974).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

BAUDRY, M., MARTRES, MP. & SCHWARTZ, JC. H1 and H2 receptors in the histamine-induced accumulation of cyclic AMP in guinea pig brain slices. Nature 253, 362–364 (1975). https://doi.org/10.1038/253362a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/253362a0

  • Springer Nature Limited

This article is cited by

Navigation