Skip to main content

Advertisement

Log in

Immunology

The thymus in the age of retirement

  • News & Views
  • Published:

From Nature

View current issue Submit your manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1: The size of the thymus decreases with increasing age.
Figure 2: Representative Vα-Jα rearrangement at the T-cell receptor (TCR) αβ locus.

References

  1. Miller, J. F. A. P. Proc. R. Soc. Lond. B. 156, 415–428 (1962).

    Google Scholar 

  2. Hammar, J. A. Arch. Anat. Physiol. Anat. Abt. S91-S182 (1906).

  3. Steinmann, G. Curr. Top. Pathol. 75, 43–80 (1986).

    Google Scholar 

  4. George, A. J. & Ritter, M. A. Immunol. Today 17, 267–272 (1996).

    Google Scholar 

  5. Mackall, C. L. & Gress, R. E. Immunol. Rev. 160, 91–102 (1997).

    Google Scholar 

  6. Muller-Hermelink, H. K., Steinmann, G. & Stein, H. Adv. Exp. Med. Biol. 149, 303–312 (1982).

    Google Scholar 

  7. Douek, D. C.et al. Nature 396, 690–695 (1998).

    Article  ADS  CAS  Google Scholar 

  8. Bogue, M. & Roth, D. B. Curr. Opin. Immunol. 8, 175–180 (1996).

    Google Scholar 

  9. Fujimoto, S. & Yamagishi, H. Nature 327, 242–243 (1987).

    Article  ADS  CAS  Google Scholar 

  10. Okazaki, K., Davis, D. D. & Sakano, H. Cell 49, 477–485 (1987).

    Google Scholar 

  11. de Villartay, J. P., Hockett, R. D., Coran, D., Korsmeyer, S. J. & Cohen, D. I. Nature 335, 170–174 (1988).

    Article  ADS  CAS  Google Scholar 

  12. Verschuren, M. C.et al. J. Immunol. 158, 1208–1216 (1997).

    Google Scholar 

  13. Livak, F. & Schatz, D. G. Mol. Cell. Biol. 16, 609–618 (1996).

    Google Scholar 

  14. Kong, F., Chen, C. H. & Cooper, M. D. Immunity 8, 97–104 (1998).

    Google Scholar 

  15. Geneser, F. Color Atlas of Histology (Munksgaard, Copenhagen, 1985).

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Rodewald, HR. The thymus in the age of retirement. Nature 396, 630–631 (1998). https://doi.org/10.1038/25251

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/25251

  • Springer Nature Limited

This article is cited by

Navigation