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Aspirin, indomethacin, catecholamine and prostaglandin interactions on rat arterioles and rabbit hearts

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Abstract

VANE et al. have demonstrated that antipyretic, anti-inflammatory drugs can inhibit prostaglandin synthesis and release1–3. We have investigated the effects of aspirin on the responses of rat arterioles to noradrenaline.

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References

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  3. Ferreira, S. H., Moncada, S., and Vane, J. R., Nature new Biol., 231, 237 (1971).

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  4. Manku, M. S., Nassar, B. A., and Horrobin, D. F., Lancet, ii, 991 (1973).

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HORROBIN, D., MANKU, M., KARMALI, R. et al. Aspirin, indomethacin, catecholamine and prostaglandin interactions on rat arterioles and rabbit hearts. Nature 250, 425–426 (1974). https://doi.org/10.1038/250425a0

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  • DOI: https://doi.org/10.1038/250425a0

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