Abstract
VANE et al. have demonstrated that antipyretic, anti-inflammatory drugs can inhibit prostaglandin synthesis and release1–3. We have investigated the effects of aspirin on the responses of rat arterioles to noradrenaline.
Similar content being viewed by others
References
Vane, J. R., Nature new Biol., 231, 232 (1971).
Smith, J. B., and Willis, A. L., Natnre new Biol., 231, 235 (1971).
Ferreira, S. H., Moncada, S., and Vane, J. R., Nature new Biol., 231, 237 (1971).
Manku, M. S., Nassar, B. A., and Horrobin, D. F., Lancet, ii, 991 (1973).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
HORROBIN, D., MANKU, M., KARMALI, R. et al. Aspirin, indomethacin, catecholamine and prostaglandin interactions on rat arterioles and rabbit hearts. Nature 250, 425–426 (1974). https://doi.org/10.1038/250425a0
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1038/250425a0
- Springer Nature Limited
This article is cited by
-
Relationship between serum prolactin concentration, vascular angiotensin sensitivity and arterial blood pressure during third trimester pregnancy
Archives of Gynecology and Obstetrics (1988)
-
Exaggerated hypotension byN-formylmethionylleucylphenylalanine in indomethacin pretreated rats. Role of toxic oxygen
Agents and Actions (1986)
-
Genetic hypertension in rats is accompanied by a defect in renal prostaglandin catabolism
Nature (1976)
-
The biochemical pathology of aspirin-induced gastric damage
Agents and Actions (1975)