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Banding and chromatid separation in Chinese hamster chromosomes

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Abstract

IN general, a chromosome exhibiting its banding pattern does not permit any internal helix to be seen, and vice versa. During studies with chromosomes of Chinese hamster cells, cultivated in vitro, it was possible to correlate G banding and spiral structure with the spatial relation between sister chromatids. G banding of human chromosomes was first described by Sumner et al.1 and later was demonstrated in the Chinese hamster chromosomes by Radabli and Kriukova2. By a hypotonic treatment, the spiralisation of the chromosomes was demonstrated by Ohnuki3 in man and later by Kato and Yoshida4 in the Chinese hamster.

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HATAMI-MONAZAH, H. Banding and chromatid separation in Chinese hamster chromosomes. Nature 249, 827–828 (1974). https://doi.org/10.1038/249827a0

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