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Quasi morphine-abstinence syndrome

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Abstract

ASSUMING that morphine induces dependence in response to continued interaction of the drug with an unidentified biochemical process of neurones, then suitable pharmacological manipulation might produce a paradigm of the morphine abstinence syndrome in experimental animals not exposed to any opiate. If so, the way in which such a quasi-abstinence syndrome was produced might throw light on the endogenous biochemical process involved1.

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Author notes

  1. G. HENDERSON

    Present address: Unit for Research on Addictive Drugs, Marischal College, University of Aberdeen, Scotland, AB9 1AS

Authors and Affiliations

  1. Miles Laboratories Ltd, Stoke Poges, Slough, Buckinghamshire, SL2 4LY, UK

    H. O. J. COLLIER, D. L. FRANCIS, G. HENDERSON & C. SCHNEIDER

Authors
  1. H. O. J. COLLIER
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  2. D. L. FRANCIS
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  3. G. HENDERSON
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  4. C. SCHNEIDER
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COLLIER, H., FRANCIS, D., HENDERSON, G. et al. Quasi morphine-abstinence syndrome. Nature 249, 471–473 (1974). https://doi.org/10.1038/249471a0

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  • DOI: https://doi.org/10.1038/249471a0

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