Abstract
Rous sarcoma virus (RSV) transforms different species of mammalian cells. The RSV genome is usually not fully expressed in such cells and the virogenic type of virus-cell interaction is obtained1,2. One exception was, however, noted by Svoboda and Klement3 in the case of some hamster tumours induced by Prague strain of RSV (PR RSV) which were found to produce traces (about 1 ID50 per 2.5 g tumour tissue) of infectious RSV.
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SVOBODA, J., DONNER, L. & MACH, O. Virus productive transformation of marsupial cells by Schmidt-Ruppin strain of RSV. Nature 248, 503–505 (1974). https://doi.org/10.1038/248503a0
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DOI: https://doi.org/10.1038/248503a0
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