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Direct physical evidence for secondary structure in an isolated fragment of R17 bacteriophage mRNA

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Abstract

The region of R17 RNA protected from RNase digestion by coat protein assumes a stable, predictable secondary structure. It seems that this structure is recognised by the protein when functioning as a translational srepressor.

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Authors and Affiliations

  1. Departments of Chemistry and Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut, 06520

    Jay Gralla, Joan A. Steitz & Donald M. Crothers

Authors
  1. Jay Gralla
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  2. Joan A. Steitz
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  3. Donald M. Crothers
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Gralla, J., Steitz, J. & Crothers, D. Direct physical evidence for secondary structure in an isolated fragment of R17 bacteriophage mRNA. Nature 248, 204–208 (1974). https://doi.org/10.1038/248204a0

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  • DOI: https://doi.org/10.1038/248204a0

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