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Platelet Contractile Regulation in an Isometric System

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A Corrigendum to this article was published on 01 August 1974

Abstract

WE have previously shown that human platelets, in addition to actomyosin, the so-called thrombosthenin1, contain a tropomyosin-like protein2. Furthermore, we provided evidence for the presence in isolated platelet actomyosin of a control system which “turns-on” the Mg-ATPase of the contractile protein complex at a saturating level of 10−6 M Ca2+ (ref. 2).

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References

  1. Bettex-Galland, M., and Lüscher, E. F., Biochim. biophys. Acta, 49, 536 (1961).

    Article  CAS  Google Scholar 

  2. Cohen, I., and Cohen, C., J. molec. Biol., 68, 383 (1972).

    Article  CAS  PubMed  Google Scholar 

  3. Grette, K., Nature, 198, 488 (1963).

    Article  ADS  CAS  PubMed  Google Scholar 

  4. Statland, B. E., Heagan, B. M., and White, J. G., Nature, 223, 521 (1969).

    Article  ADS  CAS  PubMed  Google Scholar 

  5. Majno, G., Bouvier, C. A., Gabbiani, G., Ryan, G. B., and Statkov, P., Thromb. Diath. Haemorrh., 28, 49 (1972).

    Article  CAS  PubMed  Google Scholar 

  6. Budtz-Olsen, O. E., in Clot Retraction (Blackwell Scientific Publications, Oxford, 1951).

    Google Scholar 

  7. Lüscher, E. F., Vox Sang., 1, 133 (1956).

    Article  Google Scholar 

  8. Ireland, D. M., Biochem. J., 105, 857 (1967).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Holmsen, H., and Day, H. J., J. Lab. clin. Med., 75, 841 (1970).

    Google Scholar 

  10. Rodman, N. F., and Mason, R. G., Fedn. Proc., 26, 95 (1967).

    CAS  Google Scholar 

  11. Mürer, E. H., and Holme, R., Biochim. biophys. Acta, 222, 197 (1970).

    Article  PubMed  Google Scholar 

  12. White, J. G., Blood, 31, 604 (1968).

    CAS  PubMed  Google Scholar 

  13. Day, H. J., and Holmsen, H., Ser. Haematol., 4, 3 (1971).

    CAS  PubMed  Google Scholar 

  14. Booyse, F. M., and Rafelson, jun., M. E., Ser. Haematol., 4, 152 (1971).

    CAS  PubMed  Google Scholar 

  15. Salzman, E. W., Chambers, D. A., and Neri, L. L., Nature, 210, 167 (1966).

    Article  ADS  CAS  PubMed  Google Scholar 

  16. Chambers, D. A., Salzman, E. W., and Neri, L. L., Archs. Biochem. Biophys., 119, 173 (1967).

    Article  CAS  Google Scholar 

  17. Rossi, E. S., Blood, 34, 543 (1969).

    Google Scholar 

  18. Lüscher, E. F., Probst, E., and Bettex-Galland, M., Ann. N.Y. Acad. Sci., 201, 122 (1972).

    Article  ADS  PubMed  Google Scholar 

  19. Cohen, I., Bohak, Z., de Vries, A., and Katchalski, E., Eur. J. Biochem., 10, 388 (1969).

    Article  CAS  PubMed  Google Scholar 

  20. Baenziger, N. L., Brodie, G. N., and Majerus, P. W., Proc. natn. Acad. Sci. U.S.A., 68, 240 (1971).

    Article  ADS  CAS  Google Scholar 

  21. Jamieson, G. A., Fuller, N. A., Barber, A. J., and Lombart, C., Ser. Haematol., 4, 125 (1971).

    CAS  PubMed  Google Scholar 

  22. Singer, S. J., Ann. N.Y. Acad. Sci., 195, 16 (1972).

    Article  ADS  CAS  PubMed  Google Scholar 

  23. Singer, S. J., in Structure and Function of Biological Membranes (edit. by Rothfield, L. I.), 145 (Academic Press, New York, 1971).

    Book  Google Scholar 

  24. Rubalcava, B., Martinez de Munoz, D., and Gitler, C., Biochemistry, N.Y., 8, 2742 (1969).

    Article  CAS  Google Scholar 

  25. Vanderkooi, J., and Martonosi, A., Archs. Biochem. Biophys., 133, 153 (1969).

    Article  CAS  Google Scholar 

  26. White, J. G., Krivit, W., and Vernier, R. L., Blood, 25, 241 (1965).

    CAS  PubMed  Google Scholar 

  27. Johnson, S. A., Fredell, L., Shepard, J. A., Tebo, T. H., Chang, C., Pederson, H. J., and Van Horn, D. L., in Physiology of Hemostasis and Thrombosis (edit. by Johnson, S. A., and Seegers, W. H.), 44 (Thomas, Springfield, Ill., 1967).

    Google Scholar 

  28. Cohen, I., Kaminski, E., and de Vries, A., FEBS Lett. (in the press).

  29. Chaberek, S., and Martell, A. E., Organic Sequestering Agents (Wiley, New York, 1959).

    Google Scholar 

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COHEN, I., DE VRIES, A. Platelet Contractile Regulation in an Isometric System. Nature 246, 36–37 (1973). https://doi.org/10.1038/246036a0

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  • DOI: https://doi.org/10.1038/246036a0

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