Skip to main content
SpringerLink
Log in

Post-fertilization Synthesis of Polyadenylic Acid in Sea Urchin Embryos

  • Article
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

Sea urchin embryogenesis is accompanied by polyadenylic acid [poly(A)J synthesis. Inhibition of protein synthesis and prevention of the first cleavage result in a significant increase in poly(A) content, suggesting that poly(A) synthesis occurs immediately after fertilization.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Gillespie, D., Marshall, S., and Gallo, R. C., Nature New Biology, 236, 227 (1972).

    Article  CAS  Google Scholar 

  2. Edmonds, M., and Caramela, M. G., J. Biol. Chem., 244, 1314 (1969).

    CAS  PubMed  Google Scholar 

  3. Lim, L., and Canellakis, E. S., Nature, 227, 710 (1970).

    Article  ADS  CAS  PubMed  Google Scholar 

  4. Kates, J., Cold Spring Harbor Symp. Quant. Biol., 35, 743 (1970).

    Article  CAS  Google Scholar 

  5. Lim, L., Canellakis, Z. N., and Canellakis, E. S., Biochim. Biophys. Acta, 209, 128 (1970).

    Article  CAS  PubMed  Google Scholar 

  6. Lee, S. Y., Mendecki, J., and Brawerman, G., Proc. US Nat. Acad. Sci., 68, 1331 (1971).

    Article  ADS  CAS  Google Scholar 

  7. Darnell, J. E., Wall, R., and Tushinski, R. J., Proc. US Nat. Acad. Sci., 68, 1321 (1971).

    Article  ADS  CAS  Google Scholar 

  8. Edmonds, M., Vaughan, M. H., and Nakazato, H., Proc. US Nat. Acad. Sci., 68, 1336 (1971).

    Article  ADS  CAS  Google Scholar 

  9. Burr, H., and Lingrel, J. B., Nature New Biology, 233, 41 (1971).

    Article  CAS  PubMed  Google Scholar 

  10. Darnell, J. E., Philipson, L., Wall, R., and Adesnik, M., Science, 174, 507 (1971).

    Article  ADS  CAS  PubMed  Google Scholar 

  11. Brawerman, G., Mendecki, J., and Lee, S. Y., Biochemistry, 11, 637 (1972).

    Article  CAS  PubMed  Google Scholar 

  12. Mendecki, J., Lee, S. Y., and Brawerman, G., Biochemistry, 11, 792 (1972).

    Article  CAS  PubMed  Google Scholar 

  13. Pemberton, R. E., and Baglioni, C., J. Mol. Biol., 65, 531 (1972).

    Article  CAS  PubMed  Google Scholar 

  14. Perry, R. P., La Torre, J., Kelley, D. E., and Greenberg, J. R., Biochim. Biophys. Acta, 262, 220 (1972).

    Article  CAS  PubMed  Google Scholar 

  15. Sheldon, R., Jurale, C., and Kates, J., Proc. US Nat. Acad. Sci., 69, 417 (1972).

    Article  ADS  CAS  Google Scholar 

  16. Rosenfeld, G. C., Comstock, J. P., Means, A. R., and O'Malley, B. W., Biochem. Biophys. Res. Commun., 47, 387 (1972).

    Article  CAS  PubMed  Google Scholar 

  17. Philipson, L., Wall, R., Glickman, G., and Darnell, J. E., Proc. US Nat. Acad. Sci., 68, 2806 (1971).

    Article  ADS  CAS  Google Scholar 

  18. Lai, M. M. C., and Duesberg, P. H., Nature, 235, 383 (1972).

    Article  ADS  CAS  PubMed  Google Scholar 

  19. Johnston, R. E., and Bose, H. R., Biochem. Biophys. Res. Commun., 46, 712 (1972).

    Article  CAS  PubMed  Google Scholar 

  20. Armstrong, J. A., Edmonds, M., Nakazato, H., Phillips, B. A., and Vaughan, M. H., Science, 176, 526 (1972).

    Article  ADS  CAS  PubMed  Google Scholar 

  21. Green, M., and Cartas, M., Proc. US Nat. Acad. Sci., 69, 791 (1972).

    Article  ADS  CAS  Google Scholar 

  22. Johnston, R. E., and Bose, H. R., Proc. US Nat. Acad. Sci., 69, 1514 (1972).

    Article  ADS  CAS  Google Scholar 

  23. Slater, D. W., and Spiegelman, S., Proc. US Nat. Acad. Sci., 56, 164 (1966).

    Article  ADS  CAS  Google Scholar 

  24. Slater, D. W., and Spiegelman, S., Biochim. Biophys. Acta, 213, 194 (1970).

    Article  CAS  PubMed  Google Scholar 

  25. Walker, P. M. B., in Progress in Nucleic Acid Research and Molecular Biology (edit. by Davidson, J. N., and Cohn, W. E.), 9, 301 (Academic Press, New York, 1969).

    Google Scholar 

  26. McConaughy, B. L., Laird, C. D., and McCarthy, B. J., Biochemistry, 8, 3289 (1969).

    Article  CAS  PubMed  Google Scholar 

  27. McCarthy, B. J., and Church, R. B., in Ann. Rev. Biochem., 39, 131 (1970).

    Google Scholar 

  28. Gross, P. R., and Cousineau, G. H., Biochem. Biophys. Res. Commun., 10, 321 (1963).

    Article  CAS  PubMed  Google Scholar 

  29. Gross, P. R., in Current Topics in Developmental Biology (edit. by Moscona, A. A., and Monroy, A.), 2, 1 (Academic Press, New York, 1967).

    Google Scholar 

  30. Slater, D. W., and Spiegelman, S., Biochim. Biophys. Acta, 166, 82 (1968).

    Article  CAS  PubMed  Google Scholar 

  31. Terman, S. A., Proc. US Nat. Acad. Sci., 65, 985 (1970).

    Article  ADS  CAS  Google Scholar 

  32. Raff, R. A., Colot, H. V., Selvig, S. E., and Gross, P. R., Nature, 235, 211 (1972).

    Article  ADS  CAS  PubMed  Google Scholar 

  33. Piatigorsky, J., and Whiteley, A., Biochim. Biophys. Acta, 108, 404 (1965).

    Article  CAS  PubMed  Google Scholar 

  34. Mitchison, J. M., and Cummins, J. E., J. Cell Sci., 1, 35 (1966).

    CAS  PubMed  Google Scholar 

  35. Nemer, M., Proc. US Nat. Acad. Sci., 50, 230 (1963).

    Article  ADS  CAS  Google Scholar 

  36. Gross, P. R., Malkin, L. I., and Moyer, W. A., Proc. US Nat. Acad. Sci., 51, 407 (1964).

    Article  ADS  CAS  Google Scholar 

  37. Gross, P. R., Kraemer, K., and Malkin, L. I., Biochem. Biophys. Res. Commun., 18, 569 (1965).

    Article  CAS  PubMed  Google Scholar 

  38. Kedes, L. H., and Gross, P. R., J. Mol. Biol., 42, 559 (1969).

    Article  CAS  PubMed  Google Scholar 

  39. Neyfakh, A. A., Curr. Topics Develop. Biol., 6, 45 (1971).

    Article  CAS  Google Scholar 

  40. Wilt, F. H., Develop. Biol., 23, 444 (1970).

    Article  CAS  PubMed  Google Scholar 

  41. Nemer, M., and Infante, A. A., J. Mol. Biol., 27, 73 (1967).

    Article  CAS  PubMed  Google Scholar 

  42. Slater, D. W., and Spiegelman, S., Biophys. J., 6, 385 (1966).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  43. Slater, I., Gillespie, D., and Slater, D. W., Proc. US Nat. Acad. Sci. (in the press).

  44. Malkin, L. I., Gross, P. R., and Romanoff, P., Develop. Biol., 10, 378 (1964).

    Article  CAS  PubMed  Google Scholar 

  45. Infante, A. A., and Nemer, M., Proc. US Nat. Acad. Sci., 58, 681 (1967).

    Article  ADS  CAS  Google Scholar 

  46. Kedes, L. H., Gross, P. R., Cognetti, G., and Hunter, A. L., J. Mol. Biol., 45, 337 (1969).

    Article  CAS  PubMed  Google Scholar 

  47. Epel, D., Proc. US Nat. Acad. Sci., 57, 899 (1967).

    Article  ADS  CAS  Google Scholar 

  48. Fry, B. J., and Gross, P. R., Develop. Biol., 21, 105 (1970).

    Article  CAS  PubMed  Google Scholar 

  49. Humphreys, T., Develop. Biol., 26, 201 (1971).

    Article  CAS  PubMed  Google Scholar 

  50. Laycock, D. G., and Hunt, J. A., Nature, 221, 1118 (1969).

    Article  ADS  CAS  PubMed  Google Scholar 

  51. Slater, I., and Slater, D. W., Nature New Biology, 237, 81 (1972).

    Article  CAS  PubMed  Google Scholar 

  52. Greenhouse, G. A., Hynes, R. O., and Gross, P. R., Science, 171, 686 (1971).

    Article  ADS  CAS  PubMed  Google Scholar 

  53. Giudice, G., and Horstadius, S., Exp. Cell Res., 39, 117 (1965).

    Article  CAS  PubMed  Google Scholar 

  54. Wells, R. D., and Larson, J. E., J. Mol. Biol., 49, 319 (1970).

    Article  CAS  PubMed  Google Scholar 

  55. Chamberlain, J. P., and Metz, C. B., J. Mol. Biol., 64, 593 (1972).

    Article  CAS  PubMed  Google Scholar 

  56. Waring, M. J., J. Mol. Biol., 13, 269 (1965).

    Article  CAS  PubMed  Google Scholar 

  57. Yanagisawa, T., and Isono, N., Embryologia, 9, 170 (1966).

    Article  CAS  PubMed  Google Scholar 

  58. Hogan, B., and Gross, P. R., J. Cell. Biol., 49, 692 (1971).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Author notes

  1. D. GILLESPIE

    Present address: Bionetics Research Laboratories, Bethesda, Maryland, 20014

Authors and Affiliations

  1. Cell Biology Unit, Reproduction Research Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, 20014

    D. W. SLATER & ISABEL SLATER

  2. Laboratory of Molecular Aging, Gerontology Research Center, National Institute of Child Health and Human Development, National Institutes of Health, and Baltimore City Hospitals, Baltimore, Maryland, 21224

    D. GILLESPIE

Authors
  1. D. W. SLATER
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. ISABEL SLATER
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. D. GILLESPIE
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

SLATER, D., SLATER, I. & GILLESPIE, D. Post-fertilization Synthesis of Polyadenylic Acid in Sea Urchin Embryos. Nature 240, 333–337 (1972). https://doi.org/10.1038/240333a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/240333a0

  • Springer Nature Limited

This article is cited by

Search

Navigation