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Detection of Human Leukaemia Associated Antigens in Leukaemic Serum and Normal Embryos

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Abstract

THE occurrence of tumours or leukaemia in experimental animals is frequently associated with the appearance of “new” antigens perhaps indicative of gene activation or mutation, or infection with oncogenic virus. The reliable detection of such antigens in man would provide an immunological signal of incipient tumour formation and might permit early or more precise diagnosis. The study of human tumour antigens might also be expected to yield information about the causes and natural history of human cancer as well as suggest improved means of treatment. This communication is concerned with the detection of one group of “new” antigens, those associated with human leukaemia.

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Authors and Affiliations

  1. University Department of Medical Genetics, The Royal Infirmary, Manchester, M13 9WL

    R. HARRIS

  2. Searle Research Laboratories, High Wycombe, Buckinghamshire

    D. VIZA, R. TODD, J. PHILLIPS & R. SUGAR

  3. St Mary's Hospital, Manchester, M13 0JH

    R. F. JENNISON, GRETA MARRIOTT & M. H. GLEESON

Authors
  1. R. HARRIS
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  2. D. VIZA
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  3. R. TODD
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  4. J. PHILLIPS
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  5. R. SUGAR
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  6. R. F. JENNISON
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  7. GRETA MARRIOTT
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  8. M. H. GLEESON
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HARRIS, R., VIZA, D., TODD, R. et al. Detection of Human Leukaemia Associated Antigens in Leukaemic Serum and Normal Embryos. Nature 233, 556–557 (1971). https://doi.org/10.1038/233556a0

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  • DOI: https://doi.org/10.1038/233556a0

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