Skip to main content
Log in

Para-nucleolar Position of the Human Y Chromosome in Interphase Nuclei

  • Letter
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

INDIVIDUAL human chromosomes cannot be seen during interphase, and little is known of their intra-nuclear position during most of the cell cycle. The principal exception to this has been the X chromosomes: when there is more than one, they condense during interphase to form the sex chromatin, which is often located on the nuclear membrane. It has recently become possible to locate the major portion of the Y chromosome in interphase nuclei1, and we have used this technique to demonstrate that the Y chromosome is spatially associated with the nucleolus.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Pearson, P. L., Bobrow, M., and Vosa, C. G., Nature, 226, 78 (1970).

    Article  ADS  CAS  Google Scholar 

  2. Busch, H., and Smetana, K., The Nucleolus (Academic Press, New York, 1970).

    Google Scholar 

  3. Court Brown, W. M., Human Population Cytogenetics (North-Holland, Amsterdam, 1967).

    Google Scholar 

  4. Gripenberg, U., Chromosoma, 15, 618 (1964).

    Article  CAS  Google Scholar 

  5. Ferguson-Smith, M. A., and Handmaker, S. D., Ann. Hum. Genet., 27, 143 (1963).

    Article  CAS  Google Scholar 

  6. Ferguson-Smith, M. A., Cytogenetics, 3, 124 (1964).

    Article  CAS  Google Scholar 

  7. Arrighi, F. E., and Hsu, T. C., Cytogenetics (in the press).

  8. Hsu, T. C., Brinkley, B. R., and Arrighi, F. E., Chromosoma, 23, 137 (1967).

    Article  CAS  Google Scholar 

  9. Bobrow, M., Pearson, P. L., Pike, M. C., and El-Alfi, O. S., Cytogenetics (in the press).

  10. Borgaonkar, D. S., and Hollander, D. H., Nature, 230, 52 (1971).

    Article  ADS  CAS  Google Scholar 

  11. Ferguson-Smith, M. A., Bull. Europ. Soc. Hum. Genet., 4, 39 (1970).

    Google Scholar 

  12. Pearson, P. L., Bobrow, M., Vosa, C. G., and Barlow, P. W., Nature, 231, 326 (1971).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

BOBROW, M., PEARSON, P. & COLLACOTT, H. Para-nucleolar Position of the Human Y Chromosome in Interphase Nuclei. Nature 232, 556–557 (1971). https://doi.org/10.1038/232556a0

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1038/232556a0

  • Springer Nature Limited

This article is cited by

Navigation