Abstract
Two genes encoding distinct enzymes have been functionally fused by mutation. After fusion, the two genes act as one and produce a single polypeptide chain responsible for both catalytic activities.
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YOURNO, J., KOHNO, T. & ROTH, J. Enzyme Evolution: Generation of a Bifunctional Enzyme by Fusion of Adjacent Genes. Nature 228, 820–824 (1970). https://doi.org/10.1038/228820a0
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DOI: https://doi.org/10.1038/228820a0
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