Skip to main content
SpringerLink
Log in

Synthetic DNA–RNA Hybrids and RNA–RNA Duplexes as Templates for the Polymerases of the Oncogenic RNA Viruses

  • Article
  • Published:

From Nature

View current issue Submit your manuscript

An Erratum to this article was published on 07 November 1970

Abstract

Six RNA viruses have now been shown to contain DNA polymerase activities directed by single-stranded RNA, double-stranded RNA and double-stranded DNA. It is further demonstrated that DNA–RNA hybrids, such as synthetic dC.rG, act as even more effective templates.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Temin, H. M., and Mizutani, S., Nature, 226, 1211 (1970).

    Article  ADS  CAS  Google Scholar 

  2. Baltimore, D., Nature, 226, 1209 (1970).

    Article  ADS  CAS  Google Scholar 

  3. Spiegelman, S., Burny, A., Das, M. R., Keydar, J., Schlom, J., Trávníček, M., and Watson, K., Nature, 227, 563 (1970).

    Article  ADS  CAS  Google Scholar 

  4. Spiegelman, S., Burny, A., Das, M. R., Keydar, J., Schlom, J., Trávníček, M., and Watson, K., Nature, 227, 1029 (1970).

    Article  ADS  CAS  Google Scholar 

  5. Kornberg, A., Enzymatic Synthesis of DNA, 103 (Wiley, New York and London, 1961).

    Google Scholar 

  6. Eikhom, T. S., and Spiegelman, S., Proc. US Nat. Acad. Sci., 57, 1832 (1964).

    Google Scholar 

  7. Fox, C. F., Robinson, W. S., Haselkorn, R., and Weiss, S. B., J. Biol. Chem., 239, 186 (1964).

    CAS  Google Scholar 

  8. Lee-Huang, S., and Cavalieri, L. F., Proc. US Nat Acad. Sci., 51, 1022 (1964).

    Article  ADS  CAS  Google Scholar 

  9. Chopra, H. C., Bogden, A. E., Zelljadt, J., and Jensen, C. M., Europ. J. Cancer (in the press).

  10. Gillespie, D., and Spiegelman, S., J. Mol. Biol., 12, 829 (1965).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Cancer Research, Columbia University, College of Physicians and Surgeons, 99 Fort Washington Avenue, New York, 10032

    S. SPIEGELMAN, A. BURNY, M. R. DAS, J. KEYDAR, J. SCHLOM, M. TRÁVNÍČEK & K. WATSON

Authors
  1. S. SPIEGELMAN
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. BURNY
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. R. DAS
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. J. KEYDAR
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. J. SCHLOM
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. M. TRÁVNÍČEK
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. K. WATSON
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

SPIEGELMAN, S., BURNY, A., DAS, M. et al. Synthetic DNA–RNA Hybrids and RNA–RNA Duplexes as Templates for the Polymerases of the Oncogenic RNA Viruses. Nature 228, 430–432 (1970). https://doi.org/10.1038/228430a0

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1038/228430a0

  • Springer Nature Limited

This article is cited by

Search

Navigation