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Preliminary Experiments on the Chemistry and Pharmacology of Cannabis

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Abstract

There are at least six pharmacologically effective components of cannabis. Their effects on mice include a lowering of body temperature, catalepsy, analgesia and an extension of barbiturate sleeping time, with doses from 25 to 200 mg/kg.

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GILL, E., PATON, W. & PERTWEE, R. Preliminary Experiments on the Chemistry and Pharmacology of Cannabis. Nature 228, 134–136 (1970). https://doi.org/10.1038/228134a0

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