Skip to main content

Advertisement

Log in

Postsynaptic Action of Cobra Toxin at the Myoneural Junction

  • Letter
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

RECENT investigations of peptide fractions from cobra venoms suggest that the most potent acute toxicity arises from a curare-like block of the action of acetylcholine at the skeletal myoneural junction1–3. I wish to report the effects on myoneural transmission of toxin T3 from Naja naja siamensis—(Kaouthia) (Thailand cobra) venom, a pure peptide of known amino-acid composition4.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Meldrum, B. S., Brit. J. Pharmacol., 25, 197 (1965).

    CAS  PubMed  Google Scholar 

  2. Chang, C. C., and Lee, C. Y., Brit. J. Pharmacol. Chemother., 28, 172 (1966).

    Article  CAS  Google Scholar 

  3. Tseng, L. F., Chiu, T. H., and Lee, C. Y., Toxicol. Appl. Pharmacol., 12, 526 (1968).

    Article  CAS  Google Scholar 

  4. Eaker, D., Karlsson, B., Arnberg, H., and Fryklund, L. (in preparation).

  5. Fatt, P., and Katz, B., J. Physiol., 115, 320 (1951).

    Article  CAS  Google Scholar 

  6. del Castillo, J., and Katz, B., J. Physiol., 124, 560 (1954).

    Article  CAS  Google Scholar 

  7. Martin, A. R., Physiol. Rev., 66, 51 (1966).

    Article  Google Scholar 

  8. Birks, R., Huxley, H. E., and Katz, B., J. Physiol., 150, 134 (1960).

    Article  CAS  Google Scholar 

  9. Kühne, W., Z. Biol., 23, 1 (1887).

    Google Scholar 

  10. Eaker, D., and Porath, J., J., Japan J. Microbiol., 11, 355 (1967).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

LESTER, H. Postsynaptic Action of Cobra Toxin at the Myoneural Junction. Nature 227, 727–728 (1970). https://doi.org/10.1038/227727a0

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1038/227727a0

  • Springer Nature Limited

This article is cited by

Navigation