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Increased Incorporation of 14C-Uridine into Rat Brain RNA as a Result of Novel Electroshock

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Abstract

MILD electroshock is used as an aversive stimulus in many kinds of learning experiments with rats and mice. Some workers have correlated changes in brain RNA concentration with learning1–3 so it seemed of interest to isolate, as well as possible, the elements in a learning situation and to determine their contribution to the observed changes in RNA.

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References

  1. Bowman, R. E., and Strobel, D. A., J. Comp. Phys. Psychol., 67, 448 (1969).

    Article  CAS  Google Scholar 

  2. McEwen, B. W., and Hyden, H., in Molecular Basis of Some Aspects of Mental Activity (edit. by Walaas, O.) (Academic Press, New York, 1966).

    Google Scholar 

  3. Zemp, J. W., Wilson, J. E., Schlesinger, K., Boggan, W. O., and Glassman, E., Proc. US Nat. Acad. Sci., 55, 1423 (1966).

    Article  ADS  CAS  Google Scholar 

  4. Mihailovic, L., Jankovic, B. D., Petrovic, M., and Isakovic, K., Experientia, 14, 144 (1958).

    Article  Google Scholar 

  5. Hyden, H., (1943); Yladmirov, G. E., Baranov, M. N., Pevsner, L. Z., and Wang, T. Y., (1961) cited in Macromolecules and Behavior (edit. by Gaito, J.) (Appleton, Century, Crofts, New York, 1966).

    Google Scholar 

  6. Zemp, J. W., Wilson, J. E., Schlesinger, K., Boggan, W. O., and Glassman, E., Proc. US Nat. Acad. Sci., 55, 1423 (1966).

    Article  ADS  CAS  Google Scholar 

  7. Schneider, W. C., in Methods in Enzymology, 3 (edit. by Colowick, S. P., and Kapalan, N. O.) (Academic Press, New York, 1957).

    Google Scholar 

  8. Bollum, F. J., in Procedures in Nucleic Acid Research (edit. by Cantoni, G. L., and Davies, D. R.) (Harper and Row, New York, 1966).

    Google Scholar 

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Author notes

  1. FRANK T. GARDNER

    Present address: Department of Biology, Yale University, New Haven, Connecticut

  2. RICHARD C. DEBOLD

    Present address: Psychology Department, Long Island University, New York, New York

Authors and Affiliations

  1. Wesleyan University, Middletown, Connecticut, 06457

    FRANK T. GARDNER, RICHARD C. DEBOLD, WILLIAM FIRSHEIN & HARRY W. HEERMANS jun.

Authors
  1. FRANK T. GARDNER
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  2. RICHARD C. DEBOLD
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  3. WILLIAM FIRSHEIN
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  4. HARRY W. HEERMANS jun.
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GARDNER, F., DEBOLD, R., FIRSHEIN, W. et al. Increased Incorporation of 14C-Uridine into Rat Brain RNA as a Result of Novel Electroshock. Nature 227, 1242–1243 (1970). https://doi.org/10.1038/2271242a0

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  • DOI: https://doi.org/10.1038/2271242a0

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