Abstract
THE cells of human and murine leukaemias are usually either diploid or very close to diploidy, even when their karyotypes show some specific morphological abnormalities. In a study of spontaneous and transplanted AKR leukaemias, Wakonig-Vaartaja and Stich1 found that most of the mitoses had a normal diploid set of forty chromosomes although there were forty-one chromosomes in one-third of the cases. Identical observations have been reported by Kurita and Yosida2.
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References
Wakonig-Vaartaja, R., and Stich, H. F., J. Nat. Cancer Inst., 25, 295 (1960).
Kurita, Y., and Yosida, T. H., Gann, 52, 257 (1961).
Leonard, A., and Deknudt, G. H., Nature, 214, 504 (1967).
Koller, P. C., Europ. J. Cancer, 3, 279 (1967).
Ford, C. E., in Tissue Grafting and Radiation (Academic Press, New York, 1966).
Duplan, J. F., Nouv. Revue Fr. Hémat., 2, 551 (1962).
Lejeune, J., and Berger, R., CR Acad. Sci., Paris, 263, 1880 (1966).
Lejeune, J., Berger, R., Haines, M., Lafourcade, J., Vialatte, J., Satge, P., and Turpin, R., CR Acad. Sci., Paris, 256, 1195 (1963).
De Grouchy, J., and Wolff, E., Europ. J. Cancer, 5, 159 (1969).
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LEGRAND, E., DUPLAN, J. Presence of an Additional Metacentric Chromosome in AKR/TIALD Leukaemic Cells. Nature 225, 737–738 (1970). https://doi.org/10.1038/225737a0
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DOI: https://doi.org/10.1038/225737a0
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