Abstract
WE have found that nest-building is ideally suited for the study of the effects of hallucinogenic drugs. Strains of laboratory mice differ in their nest-building activity. Males of the C57B1/6j strain (Jackson Laboratory, Bar Harbor, Maine) are very reliable in daily testing and consequently well suited for experiment. Briefly, testing involves removal of the existing nest and provision of material for a new one. After a few days of adaptation to this procedure the mouse retrieves the material and builds the new nest within a few minutes after provision of the fresh material.
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References
Shulgin, A. T., Sargent, T., and Naranjo, C., Nature 221, 537 (1969).
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SCHNEIDER, C., CHENOWETH, M. Effects of Hallucinogenic and other Drugs on the Nest-building Behaviour of Mice. Nature 225, 1262–1263 (1970). https://doi.org/10.1038/2251262a0
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DOI: https://doi.org/10.1038/2251262a0
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