Abstract
WE have compared the bronchodilator activities of aerosols of prostaglandin E1 (PGE1) and isoprenaline in the anaesthetized guinea-pig. Although PGE1 was slightly less potent than isoprenaline on intravenous administration, it had some 10–100 times the bronchodilator activity of isoprenaline when given by aerosol.
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LARGE, B., LESWELL, P. & MAXWELL, D. Bronchodilator Activity of an Aerosol of Prostaglandin E1 in Experimental Animals. Nature 224, 78–80 (1969). https://doi.org/10.1038/224078a0
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DOI: https://doi.org/10.1038/224078a0
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