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Platinum Compounds: a New Class of Potent Antitumour Agents

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Abstract

CERTAIN platinum compounds completely but reversibly iiihibit cell division in Gram-negative rods1–4. These compounds have been tested for antitumour activity and we report some of the preliminary results. The platinum compounds inhibit sarcoma 180 and leukaemia L1210 in mice.

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Authors and Affiliations

  1. Department of Biophysics,

    BARNETT ROSENBERG & LORETTA VANCAMP

  2. Natural Science Department, Michigan State University, East Lansing, Michigan

    JAMES E. TROSKO & VIRGINIA H. MANSOUR

Authors
  1. BARNETT ROSENBERG
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  2. LORETTA VANCAMP
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  3. JAMES E. TROSKO
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  4. VIRGINIA H. MANSOUR
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ROSENBERG, B., VANCAMP, L., TROSKO, J. et al. Platinum Compounds: a New Class of Potent Antitumour Agents. Nature 222, 385–386 (1969). https://doi.org/10.1038/222385a0

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  • DOI: https://doi.org/10.1038/222385a0

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