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Scanning Electron Microscopy of Healing Wounds

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Abstract

ENGINEERING techniques have shown that the apparently “healed” incised skin wound in the rat is weaker and more brittle than unwounded skin up to 5 months after the beginning of healing. Tensile strength increases with time, but there is no tendency for extensibility to recover after the first month1,2. The physical nature of the wound collagen, that is, fibre shape and weave, probably plays an important part in determining these properties3. We therefore decided to look at the structure of the wounds directly to see if this could explain the mechanical findings.

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References

  1. Forrester, J. C., Zederfeldt, B. H., Hunt, T. K., and Dunphy, J. E., Digest Seventh Intern. Conf. Med. and Biol. Eng., Session 27, page 370, Stockholm (1967).

  2. Forrester, J. C., Zederfeldt, B. H., and Hunt, T. K., J. Surg. Res. (in the press).

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Author notes

  1. J. C. FORRESTER

    Present address: Department of Surgery, University of Dundee,

Authors and Affiliations

  1. Department of Surgery, University of California School of Medicine, San Francisco

    J. C. FORRESTER & T. K. HUNT

  2. Donner Laboratory, Lawrence Radiation Laboratory, University of California, Berkeley

    T. L. HAYES

  3. Department of Electrical Engineering, University of California, Berkeley

    R. F. W. PEASE

Authors
  1. J. C. FORRESTER
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  2. T. K. HUNT
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  3. T. L. HAYES
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  4. R. F. W. PEASE
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FORRESTER, J., HUNT, T., HAYES, T. et al. Scanning Electron Microscopy of Healing Wounds. Nature 221, 373–374 (1969). https://doi.org/10.1038/221373a0

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  • DOI: https://doi.org/10.1038/221373a0

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