Abstract
NICOTINAMIDE adenine dinucleotide (NAD+) and reduced nicotinamide adenine dinucleotide (NADH) are important participants in enzymatic redox reactions1,2 (Fig. 1). Deuterium labelling experiments have shown direct and reversible transfer of hydrogen between substrate and position 4 of the nicotinamide ring of NAD+, to give one or the other of the configurations shown below3,4.
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PATEL, D. 220 MHz Proton Magnetic Resonance Spectrum of NADH. Nature 221, 1239–1241 (1969). https://doi.org/10.1038/2211239a0
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DOI: https://doi.org/10.1038/2211239a0
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