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Microbial Mutagenicity of Streptozotocin in Animal-mediated Assays

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Abstract

STREPTOZOTOCIN, a broad spectrum antibiotic with a unique structure (glucose-NHCON(NO)CH3), has several interesting properties. It is diabetogenic, carcinogenic, carcinostatic and phage-inducing1–4. It has recently been shown to be mutagenic for Salmonella typhimurium in vitro5.

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GABRIDGE, M., DENUNZIO, A. & LEGATOR, M. Microbial Mutagenicity of Streptozotocin in Animal-mediated Assays. Nature 221, 68–70 (1969). https://doi.org/10.1038/221068a0

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  • DOI: https://doi.org/10.1038/221068a0

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