Abstract
Derepression of the genome of the cancer cell may explain why certain cancer patients exhibit an isoenzyme of alkaline phosphatase biochemically and immunologically indistinguishable from human placental alkaline phosphatase.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Fishman, W. H., Inglis, N. R., Stolbach, L. L., and Krant, M. J., Cancer Res., 28, 150 (1968).
Fishman, W. H., Inglis, N. R., and Ghosh, N. K., Clin. Chim. Acta, 19, 71 (1968).
Fishman, W. H., and Ghosh, N. K., in Adv. in Clinical Chemistry, 10, 255 (1967).
Griffin, M. J., and Cox, R. R., Proc. US Nat. Acad. Sci., 56, 946 (1966).
Lancet, i, 317 (1964); ibid., i, 86 (1967).
New Eng. J. Med., 278, 1016 (1968).
Ghosh, N. K., and Fishman, W. H., Biochem. J. (in the press).
Reif, A. E., and Norris, H. J., Cancer Res., 20, 1235 (1960).
Hoppe, H. E., Bernheim, B. C., Nisalak, A., Tjio, J. H., and Smadel, J. E., J. Immunol., 91, 416 (1963).
Hayflick, L., and Moorhead, P. S., Exp. Cell Res., 25, 585 (1961).
Boyer, S. H., Ann. NY Acad. Sci., 103, 938 (1963).
Fishman, W. H., Green, S., and Inglis, N. R., Nature, 198, 685 (1963).
Fishman, W. H., and Green, S., Enzymologia, 33, 89 (1967).
Fishman, W. H., Ghosh, N. K., Inglis, N. R., and Green, S., Enzymologia (in the press).
Green, S., Giovanniello, T. J., Cote, R. A., and Fishman, W. H., Automation in Analytical Chemistry, Technicon Symposia, 1, 563 (1967).
Lipsett, M. B., Cancer Res., 25, 1068 (1965).
Bower, B. F., and Gordan, G. S., Ann. Rev. Med., 16, 83 (1965).
Hobbs, C. B., and Miller, A. L., J. Clin. Pathol., 19, 119 (1966).
Tatarinov, Y. S., Vopr. Med. Khimii, 11 (2), 20 (1965).
Alpert, M. E., Uriel, J., and deNechaud, B., New Engl. J. Med., 278, 984 (1968).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
FISHMAN, W., INGLIS, N., GREEN, S. et al. Immunology and Biochemistry of Regan Isoenzyme of Alkaline Phosphatase in Human Cancer. Nature 219, 697–699 (1968). https://doi.org/10.1038/219697a0
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1038/219697a0
- Springer Nature Limited
This article is cited by
-
Enzymatic formation of curcumin in vitro and in vivo
Nano Research (2018)
-
In situ generated D‐peptidic nanofibrils as multifaceted apoptotic inducers to target cancer cells
Cell Death & Disease (2017)
-
Alkaline Phosphatase: An Overview
Indian Journal of Clinical Biochemistry (2014)
-
A combined approach to data mining of textual and structured data to identify cancer-related targets
BMC Bioinformatics (2006)
-
Induction of alkaline phosphatase generation by il-1β and LPS on human neutrophils and macrophages and lack of inhibition by interleukin-1 receptor antagonist
Inflammopharmacology (1995)