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Induction of Hyperluteinization and Precocious Opening of the Vagina in Rats with a Transverse Cut in the Hypothalamus made shortly after Birth

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Abstract

THERE have been several reports that electrolytic lesions in the hypothalamus of infantile rats result in a precocious opening of the vagina and eventually in an early luteinization of the ovary1–5. It seems that in all cases when the ovaries of animals bearing hypothalamic lesions contained corpora lutea at puberty there was no more than the usual number of these bodies.

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Authors and Affiliations

  1. Boris Kidrič Institute of Nuclear Sciences, PO Box 522, Belgrade, Yugoslavia

    PETAR N. MARTINOVITCH, OLIVERA K. IVANIŠEVIČ & JOVAN V. MARTINOVIČ

  2. Institute for Biological Research, 29 Novembra 142, Belgrade, Yugoslavia

    PETAR N. MARTINOVITCH, OLIVERA K. IVANIŠEVIČ & JOVAN V. MARTINOVIČ

Authors
  1. PETAR N. MARTINOVITCH
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  2. OLIVERA K. IVANIŠEVIČ
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  3. JOVAN V. MARTINOVIČ
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MARTINOVITCH, P., IVANIŠEVIČ, O. & MARTINOVIČ, J. Induction of Hyperluteinization and Precocious Opening of the Vagina in Rats with a Transverse Cut in the Hypothalamus made shortly after Birth. Nature 217, 866–867 (1968). https://doi.org/10.1038/217866a0

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  • DOI: https://doi.org/10.1038/217866a0

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