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Reconstruction of Three Dimensional Structures from Electron Micrographs

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Abstract

General principles are formulated for the objective reconstruction of a three dimensional object from a set of electron microscope images. These principles are applied to the calculation of a three dimensional density map of the tail of bacteriophage T4.

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Authors and Affiliations

  1. MRC Laboratory of Molecular Biology, Hills Road, Cambridge

    D. J. DE ROSIER & A. KLUG

Authors
  1. D. J. DE ROSIER
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  2. A. KLUG
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DE ROSIER, D., KLUG, A. Reconstruction of Three Dimensional Structures from Electron Micrographs. Nature 217, 130–134 (1968). https://doi.org/10.1038/217130a0

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