Abstract
In a simulated blood plasma ‘FX-80’, a liquid fluorocarbon with a high solubility for oxygen, maintains the electrical activity of a preparation of isolated rat brain. This is as effective as a suspension of erythrocytes in the same simulated blood plasma.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Burk, D., Hearon, J., Caroline, L., and Schade, A. L., J. Biol. Chem., 165, 723 (1946).
Michaelis, L., Arch. Biochem., 17, 201 (1948).
Drabkin, D. L., Science, 101, 445 (1945).
Clark, L. C., and Gollan, F., Science, 152, 1755 (1966).
Gollan, F., and Clark, L. C., The Physiologist, 9, 191 (1966).
Andjus, R., Suhara, K., and Sloviter, H. A., J. Appl. Physiol., 22, 1033 (1967).
Horn, H. D., and Bruns, F. H., Biochim. Biophys. Acta, 21, 378 (1956).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
SLOVITER, H., KAMIMOTO, T. Erythrocyte Substitute for Perfusion of Brain. Nature 216, 458–460 (1967). https://doi.org/10.1038/216458a0
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1038/216458a0
- Springer Nature Limited
This article is cited by
-
Perfluorocarbon-based oxygen carriers: from physics to physiology
Pflügers Archiv - European Journal of Physiology (2021)
-
Cholesterol-like effects of a fluorotelomer alcohol incorporated in phospholipid membranes
Scientific Reports (2018)
-
Comprehensive bioimaging with fluorinated nanoparticles using breathable liquids
Nature Communications (2015)
-
Blood Substitutes: Possibilities with Nanotechnology
Indian Journal of Hematology and Blood Transfusion (2014)
-
First- and second-generation perfluorocarbon emulsions
Pharmaceutical Chemistry Journal (2009)