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Suppression of Natural Haemolysin Titre in Rabbits exposed Daily to Gamma Radiation

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Abstract

ACUTE whole body X-irradiation of rabbits with 300–700 r. depresses the synthesis of natural anti-sheep (anti-Forssman) haemolysin1,2. This serum antibody, which occurs normally, is thought to arise in response to small amounts of related Forssman antigens entering from the rabbit's environment3. Recovery begins about 2 weeks after irradiation and normal or enhanced haemolysin titres are usually reached in a few more weeks2,4. A second irradiation provokes a second sequence of depression and recovery4. This resilience following acute irradiations prompted a study of the extent to which haemolysin production could withstand injury sustained during protracted irradiation with small daily exposures.

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Authors and Affiliations

  1. Radiation Biology Section, Laboratory of Physiology, National Cancer Institute, Bethesda, Maryland

    LAURENCE R. DRAPER

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  1. LAURENCE R. DRAPER
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DRAPER, L. Suppression of Natural Haemolysin Titre in Rabbits exposed Daily to Gamma Radiation. Nature 215, 848–849 (1967). https://doi.org/10.1038/215848a0

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  • DOI: https://doi.org/10.1038/215848a0

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