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Crossover Model of Antibody Variability

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Abstract

Several unsatisfactory models have been proposed to account for the variation in the primary structure of the polypeptide chains in the antibody molecule. A new model is proposed here; it is based on intrachromosomal crossing over during the development of plasma cells.

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Author notes

  1. H. L. K. WHITEHOUSE

    Present address: Division of Biology, Southwest Center for Advanced Studies, Dallas, Texas

Authors and Affiliations

  1. Department of Botany, University of Cambridge,

    H. L. K. WHITEHOUSE

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  1. H. L. K. WHITEHOUSE
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WHITEHOUSE, H. Crossover Model of Antibody Variability. Nature 215, 371–374 (1967). https://doi.org/10.1038/215371a0

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  • DOI: https://doi.org/10.1038/215371a0

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