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Differentiation of Receptor Systems activated by Sympathomimetic Amines

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Abstract

CLASSIFICATION of receptor systems which are activated by sympathomimetic amines has engaged the attention of many investigators. Ahlquist1–3 has suggested the convenient designations of alpha (α) and beta (β) to distinguish major differences in the responses elicited in various organ systems. Our investigations have provided results which cannot be explained easily on the assumption that the β-type designates a single receptor population4–6. We now report additional studies which show that two distinct receptor types are at present included within this group.

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Authors and Affiliations

  1. Sterling-Winthrop Research Institute, Rensselaer, New York

    A. M. LANDS, A. ARNOLD, J. P. MCAULIFF, F. P. LUDUENA & T. G. BROWN JUN.

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  1. A. M. LANDS
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  2. A. ARNOLD
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  3. J. P. MCAULIFF
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  4. F. P. LUDUENA
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  5. T. G. BROWN JUN.
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LANDS, A., ARNOLD, A., MCAULIFF, J. et al. Differentiation of Receptor Systems activated by Sympathomimetic Amines. Nature 214, 597–598 (1967). https://doi.org/10.1038/214597a0

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