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Bone Marrow and Lymphoid Cell Injection of the Pig Foetus resulting in Transplantation Tolerance or Immunity, and Immunoglobulin Production

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Abstract

IT is known that the pig is capable at birth of immune responses to some antigens (phage1,2; animal viruses3–5; toxoids6; and homografts7,8). The finding that thymectomy in neonatal pigs is without effect on homograft rejection8 also suggests that the pig, unlike many laboratory rodents9,10 acquires the faculty of graft rejection before birth. Information on immune responses of pig foetuses to injected antigens has not been found in the literature. This communication outlines such research.

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Authors and Affiliations

  1. Department of Experimental Pathology, A.R.C. Institute of Animal Physiology, Babraham, Cambridge

    R. M. BINNS

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  1. R. M. BINNS
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BINNS, R. Bone Marrow and Lymphoid Cell Injection of the Pig Foetus resulting in Transplantation Tolerance or Immunity, and Immunoglobulin Production. Nature 214, 179–181 (1967). https://doi.org/10.1038/214179a0

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