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Assembly of Semliki Forest Virus in Brain

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Abstract

Specialized methods of combined light and electron microscopy of brains of suckling mice show stages in assembly of virus, and associated neuropathology. In neuronal cytoplasm virus cores cluster on cisterna membranes and obtain their protein coat in a way which suggests that viral RNA and cisternal membrane provide a system for protein synthesis.

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MCGEE-RUSSELL, S., GOSZTONYI, G. Assembly of Semliki Forest Virus in Brain. Nature 214, 1204–1206 (1967). https://doi.org/10.1038/2141204a0

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  • DOI: https://doi.org/10.1038/2141204a0

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