Skip to main content
Log in

Preleukaemic Syndrome in Germfree AKR Mice

  • Article
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

Some mice of the AKR strain reared under germfree conditions become thin and “hunched up”, with rough wet fur, depilation around the anus, shrunken thymus and enlarged lymph nodes. The histological appearance of the thymus and lymphoid tissue is similar to that in the early stages of mouse leukaemia

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Glimstedt, G., Nord. Med. Tidskr., 14, 1269 (1937).

    Google Scholar 

  2. Gordon, H. A., Ann. N.Y. Acad. Sci., 78, 208 (1959).

    Article  ADS  CAS  Google Scholar 

  3. Thorbecke, G. J., Ann. N.Y. Acad. Sci., 78, 237 (1959).

    Article  ADS  CAS  Google Scholar 

  4. Bauer, H., Horowitz, R. E., Levenson, S. M., and Popper, H., Amer. J. Pathol., 42, 471 (1963).

    CAS  Google Scholar 

  5. Dunn, T. B., J. Nat. Cancer Inst., 14, 1281 (1954).

    CAS  PubMed  Google Scholar 

  6. Grabar, P., Courcon, J., and Wostmann, B. S., J. Immunology, 88, 679 (1962).

    CAS  Google Scholar 

  7. Wostmann, B. S., Ann. N.Y. Acad. Sci., 78, 254 (1959).

    ADS  CAS  PubMed  Google Scholar 

  8. Bealmear, M., and Wilson, R., Anat. Rec., 154, 261 (1966).

    Article  CAS  Google Scholar 

  9. de Harven, E., J. Exp. Med., 120, 857 (1964).

    Article  CAS  Google Scholar 

  10. Pollard, M., and Matsuzawa, T., Proc. Soc. Exp. Biol. and Med., 16, 967 (1964).

    Article  Google Scholar 

  11. Kajima, M., and Pollard, M., J. Bact., 90, 1448 (1965).

    CAS  PubMed  Google Scholar 

  12. Wagner, M., Ann. N.Y. Acad. Sci., 78, 89 (1959).

    Article  ADS  Google Scholar 

  13. Gilbey, J. G., and Pollard, M., J. Nat. Cancer Inst. (in the press).

  14. Pollard, M., Teah, B. A., and Matsuzawa, T., Proc. Soc. Exp. Biol. and Med., 120, 72 (1965).

    Article  CAS  Google Scholar 

  15. Krum bhaar, E. B., Blood, 3, 953 (1948).

    CAS  Google Scholar 

  16. Simonsen, M., Engelbreth-Holm, J., Jensen, E., and Poulsen, H., Ann. N.Y. Acad. Sci., 73, 834 (1958).

    Article  ADS  CAS  Google Scholar 

  17. Siskind, G. W., and Thomas, L., J. Exp. Med., 110, 511 (1959).

    Article  CAS  Google Scholar 

  18. Simonsen, M., Acta Pathol. and Microbiol. Scand., 40, 480 (1957).

    MathSciNet  CAS  Google Scholar 

  19. Billingham, R. E., Ann. N.Y. Acad. Sci., 73, 782 (1958).

    Article  ADS  CAS  Google Scholar 

  20. Siegler, R., and Rich, M. A., Cancer Res., 23, 1669 (1963).

    CAS  PubMed  Google Scholar 

  21. Pollard, M., Bact. Proc., 134 (1964).

  22. Dameshek, W., Israel J. Med. Sci., 1, 1304 (1965).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

POLLARD, M. Preleukaemic Syndrome in Germfree AKR Mice. Nature 213, 142–144 (1967). https://doi.org/10.1038/213142a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/213142a0

  • Springer Nature Limited

This article is cited by

Navigation