Abstract
THE nature of molecular interactions in the lipoprotein complexes of biological membranes has been a subject under active enquiry for many years. The classical Davson-Danielli paucimolecular model1 postulates apolar mutual interaction between the lipid molecules and electrostatic binding of the lipid with the structural protein. Although this model has received support from biophysical studies, especially on myelin2,3, there is other experimental evidence which suggests that extensive hydrophobic binding may occur between lipids and proteins, for example, from studies on mitochondria4,5, halobacterium halobium6, erythrocyte ghosts7, plasma membrane fragments of Ehrlich ascites cells (D. F. H. Wallach and P. H. Zahler, personal communication) and chloroplast lamellae8.
Similar content being viewed by others
References
Danielli, J. F., and Davson, H. A., J. Cell. Comp. Physiol., 5, 495 (1935).
Schmitt, F. O., Bear, R. S., and Palmer, K. J., J. Cell. Comp. Physiol., 18, 31 (1941).
Finean, J. B., Intern. Rev. Cytol., 12, 303 (1961).
Green, D. E., and Fleischer, S., Biochim. Biophys. Acta, 70, 554 (1963).
Richardson, S., Hultin, H. D., and Fleischer, S., Arch. Biochem. Biophys., 105, 254 (1964).
Brown, A. D., J. Mol. Biol., 12, 491 (1965).
Maddy, A. H., and Malcom, B. R., Science, 150, 1616 (1965).
Ke, B., Arch. Biochem. Biophys., 112, 554 (1965).
Chapman, D., and Penkett, S. A., Nature, 211, 1304 (1966).
Dodge, J. J., Mitchell, C., and Hanahan, D. J., Arch. Biochem. Biophys., 100, 119 (1963).
Kowalsky, A., J. Biol. Chem., 237, 1807 (1962).
Eylar, E. H., Madoff, M. A., Brody, O. V., and Oncley, J. L., J. Biol. Chem., 237, 1992 (1962).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
CHAPMAN, D., KAMAT, V., DE GIER, J. et al. Nuclear Magnetic Resonance Spectroscopic Studies of Erythrocyte Membranes. Nature 213, 74–75 (1967). https://doi.org/10.1038/213074a0
Received:
Issue Date:
DOI: https://doi.org/10.1038/213074a0
- Springer Nature Limited
This article is cited by
-
Nuclear Relaxation in Phospholipids and Biological Membranes
Nature (1970)
-
Magnetic Relaxation in Ordered Systems
Nature (1970)