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Kinetics of Glucose-6-phosphate as an Inhibitor of Phosphofructokinase

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Abstract

IN the course of an enzyme investigation of the psoriatic epidermis1, it seemed possible that epidermal phospho-fructokinase (PFK) may be inhibited by glucose-6-phosphate (G-6-P). Since the latter is the precursor of the substrate, fructose-6-phosphate (F-6-P), the following reactions must be taken into account with crude enzyme extracts

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References

  1. Hasegawa, J., J. Invest. Dermatol. (in the press).

  2. Dixon, M., and Webb, E. C., Enzymes, 319, second ed. (Academic Press, New York, 1964).

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Authors and Affiliations

  1. Department of Dermatology, Northwestern University Medical School and Veterans Administration Research Hospital, Chicago

    J. HASEGAWA

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  1. J. HASEGAWA
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HASEGAWA, J. Kinetics of Glucose-6-phosphate as an Inhibitor of Phosphofructokinase. Nature 212, 940–941 (1966). https://doi.org/10.1038/212940a0

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