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Lysosome Stabilizing Agents for Hypothermic Kidney Preservation

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Abstract

THE recent enthusiasm for organ transplantation has stimulated increased investigation into the problems of organ storage. In particular, the kidney is being extensively studied because of the clinical need for and apparent success of renal transplants. A complex organ such as the kidney presents many difficulties in the determination of success of preservation, as failure in one system of organ function may compromise the physiological performance of the whole transplanted organ. It is, therefore, desirable to study function in as many component systems as are available.

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LOTKE, P. Lysosome Stabilizing Agents for Hypothermic Kidney Preservation. Nature 212, 512–513 (1966). https://doi.org/10.1038/212512a0

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