Abstract
PREVIOUSLY1, it was shown that treatment of human red cells with crystalline trypsin in a low concentration resulted in destruction of the I agglutinogen on their cells and release of a sialoglycopeptide with the I activity. This communication describes the isolation and some chemical properties of the sialoglycopeptide.
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Ohkuma, S., and Ikemoto, S., Proc. Japan Acad., 41, 482 (1965).
Ohkuma, S., Shinohara, T., and Miyauchi, C., Nature, 207, 527 (1965).
Ohkuma, S., Shinohara, T., and Miyauchi, C., Proc. Japan Acad., 41, 332 (1965).
McGuckin, W. F., and McKenzie, B. F., Clin. Chem., 4, 476 (1958).
Grassmann, W., and Hannig, K., Hoppe-Seyler's Z. Physiol. Chem., 290, 1 (1952).
Jeanes, A., Wise, C. S., and Dimler, R. J., Anal. Chem., 23, 415 (1951).
Eylar, E. H., and Jeanloz, R. W., J. Biol. Chem., 237, 622 (1962).
Ohkuma, S., and Shinohara, T., Nature, 202, 593 (1964).
Svennerholm, E., and Svennerholm, L., Nature, 181, 1154 (1958).
Gottschalk, A., and Graham, E. R. B., Biochim. Biophys. Acta, 34, 380 (1959).
Cook, G. M. W., Heard, D. H., and Seaman, G. V. F., Nature, 188, 1011 (1960).
Cook, G. M. W., Nature, 195, 159 (1962).
Eylar, E. H., and Madoff, M. A., Fed. Proc., 21, 402 (1962).
Marcus, D. M., Kabat, E. A., and Rosenfield, R. E., J. Exp. Med., 118, 175 (1963).
Iseki, S., and Okada, S., Proc. Japan Acad., 27, 455 (1951).
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OHKUMA, S., IKEMOTO, S. A Sialoglycopeptide liberated from Human Red Cells by Treatment with Trypsin. Nature 212, 198–199 (1966). https://doi.org/10.1038/212198a0
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DOI: https://doi.org/10.1038/212198a0
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