Abstract
YOUNG1 has described two types of synapses in the stellate ganglion of the squid, both of which are of great physiological interest. The first is a set of uniquely large synapses formed by the contacts between branches of a giant preganglionic fibre and the giant axons in the stellar nerves. The other consists of a large number of small contacts which the preganglionic fibres make with small nerve fibres which then fuse to form the giant axons. It now seems quite certain2–4 that the transmission of impulses across both types of synapses is effected by the release of a transmitter substance.
Similar content being viewed by others
References
Young, J. Z., Phil. Trans. Roy. Soc., B, 229, 465 (1939).
Hagiwara, S., and Tasaki, I., J. Physiol., 143, 114 (1958).
Takeuchi, A., and Takeuchi, N., J. Gen. Physiol., 45, 1181 (1962).
Miledi, R., and Slater, C. R., J. Physiol., 184, 473 (1966).
Katz, B., Proc. Roy. Soc., B, 155, 455 (1962).
Katz, B., and Thesleff, S., J. Physiol., 137, 267 (1957).
Katz, B., and Miledi, R., J. Physiol., 168, 389 (1963).
Narahashi, T., Moore, J. W., and Scott, W. R., J. Gen. Physiol., 47, 965 (1964).
Nakamura, Y., Nakajima, S., and Grundfest, H., J. Gen. Physiol., 48, 985 (1965).
Furukawa, T., Sasaoka, T., and Mosoya, Y., Jap. J. Physiol., 9, 143 (1959).
Elmquist, D., and Feldman, D. S., Acta Physiol. Scand., 64, 475 (1965).
Katz, B., and Miledi, R., Nature, 207, 1097 (1965).
Katz, B., and Miledi, R., Nature (following communication)
Katz, B., and Miledi, R., J. Physiol., 185, 5P (1966).
Takeuchi, A., and Takeuchi, N., J. Physiol., 170, 296 (1964).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
MILEDI, R. Miniature Synaptic Potentials in Squid Nerve Cells. Nature 212, 1240–1242 (1966). https://doi.org/10.1038/2121240a0
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1038/2121240a0
- Springer Nature Limited
This article is cited by
-
A simplified memory network model based on pattern formations
Scientific Reports (2014)
-
Ricardo Miledi and the calcium hypothesis of neurotransmitter release
Nature Reviews Neuroscience (2002)