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The Fujiwara Reaction : Some Observations on the Mechanism

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Abstract

WHEN certain 1 : 1 : 1-trichloro-compounds are heated in the presence of pyridine and aqueous caustic alkali, a red colour is imparted to the pyridine layer1,2. The reaction is extremely sensitive. The nature of the red material has not been fully elucidated, but the following mechanism has been proposed3:

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References

  1. Fujiwara, K., Sitzber. Abhandel. naturforsch Ges. Rostock, 6, 33 (1914).

    Google Scholar 

  2. Ross, J. H., J. Biol. Chem., 58, 641 (1923).

    CAS  Google Scholar 

  3. Feigl, F., Spot Tests in Organic Analysis, fifth ed., 313 (Elsevier, London, 1956).

    Google Scholar 

  4. Curry, A. S., Toxicology, Mechanisms and Analytical Methods, 1, 261, edit. by Stewart, C. P., and Stolman, A. (Academic Press, London and New York, 1960).

    Google Scholar 

  5. Marshall, jun., E. K., and Owens, jun., A. H., Bull. Johns Hopkins Hosp., 95, 1 (1954).

    CAS  PubMed  Google Scholar 

  6. Borker, E., Stefanucci, A., and Vitti, J., Anal. Chem., 35, 1321 (1963).

    Article  CAS  Google Scholar 

  7. Seto, A., and Schultze, M. D., Anal. Chem., 28, 1625 (1956).

    Article  CAS  Google Scholar 

  8. Friedman, P. J., and Cooper, J. R., Anal. Chem., 30, 1165 (1958).

    Article  Google Scholar 

  9. Butler, T. C., J. Pharmacol. and Exp. Therap., 92, 49 (1948).

    CAS  Google Scholar 

  10. Cohen, J. B., Theoretical Organic Chemistry, 142 and 150 (Macmillan, London, 1928).

    Google Scholar 

  11. Schwarzenbach, G., Lutz, K., and Felder, E., Helv. Chim. Acta, 27, 576 (1944).

    Article  CAS  Google Scholar 

  12. Mantel, M., Molco, M., and Stiller, M., Anal. Chem., 35, 1337 (1963).

    Article  Google Scholar 

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Authors and Affiliations

  1. Forensic Laboratory, Equine Research Station, Newmarket, Suffolk

    M. S. MOSS & H. J. RYLANCE

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  1. M. S. MOSS
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  2. H. J. RYLANCE
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MOSS, M., RYLANCE, H. The Fujiwara Reaction : Some Observations on the Mechanism. Nature 210, 945–946 (1966). https://doi.org/10.1038/210945a0

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