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Toxicity of Dimethyl Sulphoxide to the Goldfish, Carassius auratus

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Abstract

INVESTIGATIONS of the comparative toxicities of organic pesticides to fish have to some extent been hampered by the insolubility of these compounds in water. The most widely used solvent in such tests is acetone, but this compound has important disadvantages. Although it is relatively non-toxic to fish (in this laboratory goldfish have tolerated 18 p.p.t. for at least one week) acetone in solution has a high oxygen demand which may lead to oxygen depletion in the test media1,2, and if the compound under evaluation, or the solvent vehicle, is volatile it is clearly undesirable to rely on artificial oxygenation.

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References

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BALL, I. Toxicity of Dimethyl Sulphoxide to the Goldfish, Carassius auratus. Nature 210, 639–640 (1966). https://doi.org/10.1038/210639b0

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