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Vitamin B12 Concentrations in Human Tissues

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Abstract

THE development of microbiological technique for evaluating vitamin B12 concentration has made it possible to measure the wide variations in the quantity of vitamin B12 present in sera from humans in normal and various pathological states. By this means, the concentration of serum B12 has been found to be above normal in hepatitis1, cirrhosis2 and myelogenous leukaemia3, but below normal in pernicious anaemia4, total gastrectomy5, sprue6, old age7 and pregnancy8.

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Authors and Affiliations

  1. Biochemistry Research Laboratory, Veterans Administration Hospital, Baltimore, Maryland

    JENG M. HSU

  2. Radioisotope Research Laboratory, Veterans Administration Hospital, Washington, D.C.

    BERGENE KAWIN

  3. Clinical Laboratory, St. Joseph's Hospital, Elmira, New York

    PHYLLIS MINOR & JAMES A. MITCHELL

Authors
  1. JENG M. HSU
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  2. BERGENE KAWIN
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  3. PHYLLIS MINOR
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  4. JAMES A. MITCHELL
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HSU, J., KAWIN, B., MINOR, P. et al. Vitamin B12 Concentrations in Human Tissues. Nature 210, 1264–1265 (1966). https://doi.org/10.1038/2101264a0

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