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Liberation of Adenine from Deoxyribonucleic Acid by Hydrogen Peroxide

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Abstract

RECENTLY1, we have established a metabolic cycle producing virogens and mutagens, in which hydrogen peroxide performs a central function. It is assumed that these virogenic and mutagenic metabolites can act on nucleic acids in cells. We have now demonstrated that adenine is specifically liberated from deoxyribonucleic acid molecule by the action of hydrogen peroxide.

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References

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Authors and Affiliations

  1. Agricultural Chemistry Institute, Kyushu University, Fukuoka, Japan

    KAZUO YAMAFUJI & YASUSHI UCHIDA

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  1. KAZUO YAMAFUJI
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  2. YASUSHI UCHIDA
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YAMAFUJI, K., UCHIDA, Y. Liberation of Adenine from Deoxyribonucleic Acid by Hydrogen Peroxide. Nature 209, 301–302 (1966). https://doi.org/10.1038/209301a0

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