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Substrate-utilization of the Human Kidney

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Abstract

COMPARED with other organs such as the heart and the brain, the human kidney has a copious blood-flow and a high oxygen consumption (weight for weight). In the secretion of urine, active energy-consuming processes play an important part, in addition to the purely physical processes of ultrafiltration and back diffusion. Hitherto, it has not been established whether this energy is made available by anaerobic or by aerobic metabolic processes. So far, only a correlation between oxygen consumption and sodium reabsorption has been demonstrated by Deetjen et al.1 and by Lassen et al.2 in animal experiments.

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  1. Medical University Hospital, Tübingen, Germany

    H. NIETH & P. SCHOLLMEYER

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  1. H. NIETH
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  2. P. SCHOLLMEYER
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NIETH, H., SCHOLLMEYER, P. Substrate-utilization of the Human Kidney. Nature 209, 1244–1245 (1966). https://doi.org/10.1038/2091244a0

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