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Strain Differences in Mouse Mammary Tissue Sensitivity to Prolactin and Somatotrophin in Organ Culture

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Abstract

THE lactogenic activities of ovine prolactin and bovine somatotrophin have been investigated in several strains of inbred mice, and a spectrum of responses was reported1,2. Prolactin was lactogenic in all strains, with some variations in sensitivity encountered. On the other hand, whereas somatotrophin showed considerable activity on tissues from some strains, other strains were much less reactive, and a single strain was completely unresponsive to the lactogenic effects of this hormone.

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Authors and Affiliations

  1. Department of Zoology and its Cancer Research Genetics Laboratory, University of California, Berkeley, California

    EVELYN M. RIVERA

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  1. EVELYN M. RIVERA
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RIVERA, E. Strain Differences in Mouse Mammary Tissue Sensitivity to Prolactin and Somatotrophin in Organ Culture. Nature 209, 1151–1152 (1966). https://doi.org/10.1038/2091151a0

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